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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL1 All Species: 27.58
Human Site: Y376 Identified Species: 50.56
UniProt: P28749 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28749 NP_002886.2 1068 120847 Y376 T P L T G R R Y L R E K E A V
Chimpanzee Pan troglodytes XP_001139919 1068 120960 Y376 T P L T G R R Y L R E K E A V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534412 1068 120563 Y376 T P L T G R R Y L R E K E A V
Cat Felis silvestris
Mouse Mus musculus Q64701 1063 119481 Y376 T P L T G R R Y L Q E K E A V
Rat Rattus norvegicus O55081 1135 127799 Y405 N P L T G V R Y V Q E N S P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 Y348 T P L T G R N Y I K E S S P Y
Chicken Gallus gallus Q90600 921 104417 D260 A S K Q I D T D T K V I E I L
Frog Xenopus laevis NP_001084880 998 113114 Y330 T P L T G R G Y L K E E Q T V
Zebra Danio Brachydanio rerio NP_001124082 1058 120023 Y377 T P L T G R R Y L K E K E V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 C184 G N H A H G K C S Y I K L D D
Honey Bee Apis mellifera XP_395096 1006 113492 D341 T Q M M N V G D L H E Q F Q M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q3LXA7 1010 111475 L318 G L T V F K D L L Q G D S L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 D330 S L I T L E K D Y Y D G K G E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 95 N.A. 90.3 48.9 N.A. 52.8 22.1 63.9 63.2 N.A. 25.4 43.1 N.A. N.A.
Protein Similarity: 100 99.8 N.A. 98 N.A. 95.6 65.9 N.A. 69.7 37.8 77.3 77 N.A. 44.4 63.2 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 46.6 N.A. 53.3 6.6 66.6 80 N.A. 6.6 20 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 60 N.A. 66.6 20 86.6 93.3 N.A. 13.3 40 N.A. N.A.
Percent
Protein Identity: N.A. 25 N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. 43.9 N.A. 42 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 0 0 0 0 0 0 0 31 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 8 8 24 0 0 8 8 0 8 8 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 70 8 47 0 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 16 0 0 0 62 8 16 0 0 0 8 8 0 8 0 % G
% His: 0 0 8 0 8 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 8 0 8 8 0 8 0 % I
% Lys: 0 0 8 0 0 8 16 0 0 31 0 47 8 0 8 % K
% Leu: 0 16 62 0 8 0 0 8 62 0 0 0 8 8 16 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 8 0 0 8 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 0 62 0 0 0 0 0 0 0 0 0 0 0 16 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 24 0 8 8 8 0 % Q
% Arg: 0 0 0 0 0 54 47 0 0 24 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 0 0 0 8 0 0 8 24 0 0 % S
% Thr: 62 0 8 70 0 0 8 0 8 0 0 0 0 8 0 % T
% Val: 0 0 0 8 0 16 0 0 8 0 8 0 0 8 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 8 16 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _